The following video clips are highlights from the 2022 ESSKA Consensus on the Use of Injectable Orthobiologics for Knee Osteoarthritis, Part 1 - Blood-derived Products (PRP).

Clip downloads can be ordered from the ON Foundation office

Introduction: Motivation

What is the motivation behind the ORBIT consensus project?

Speaker: Lior Laver

Publication: ESSKA ORBIT Consensus Report

Introduction: Methodology

Which Methodology did the consensus team use?

Speaker: Lior Laver

Publication: ESSKA ORBIT Consensus Report

Introduction: Definition of "Blood Derived Products"

How does the consensus team define "Blood Derived Products"?

Speaker: Laura de Girolamo

Publication: ESSKA ORBIT Consensus Report

PRP Rationale/ Indications: Current clinical evidence

Does current clinical evidence support the use of PRP for knee OA?

Speaker: Lior Laver

Publication: ESSKA ORBIT Consensus Report

Indications: Best indication for PRP in OA knee

For which degrees of knee OA is PRP best indicated?

Speaker: Giuseppe Filardo

Publication: ESSKA ORBIT Consensus Report

Indications: Use of PRP in PFOA treatment

Is PRP indicated for the treatment of Patellofemoral OA (PFOA)?

Speaker: Laura de Girolamo

Publication: ESSKA ORBIT Consensus Report

Indications: recommended age range for PRP

For what age range is PRP recommended?

Speaker: Elizaveta Kon

Publication: ESSKA ORBIT Consensus Report

Indications: PRP use in inflammatory phase

Could PRP for knee OA be used during the inflammatory phase when joint effusion is present (following effusion aspiration)?

Speaker: Thomas Tischer

Publication: ESSKA ORBIT Consensus Report

Indications: repeated cycle of PRP injections following successful treatment

Is a repeated cycle of PRP injections recommended following a previous successful PRP treatment for knee OA upon the re-emergence of symptoms?

Speaker: Mikel Sanchez

Publication: ESSKA ORBIT Consensus Report

Indications: PRP use in asymptomatic knee

Is there rationale in injecting PRP in asymptomatic early knee OA?

Speaker: Elizaveta Kon

Publication: ESSKA ORBIT Consensus Report

Indications: PRP vs. Corticosteroids

Are there advantages of PRP use in comparison to Corticosteroids for treating knee OA?

Speaker: Lior Laver

Publication: ESSKA ORBIT Consensus Report

Indications: PRP vs. hyaluronic acid

Is PRP a clinically better injectable option than hyaluronic acid for the treatment of knee OA?

Speaker: Lior Laver

Publication: ESSKA ORBIT Consensus Report

Indications: disease-modifying effects in knee OA due to PRP

Does PRP induce disease-modifying effects in knee OA?

Speaker: Giuseppe Filardo

Publication: ESSKA ORBIT Consensus Report

Characterization: LR-PRP vs. LP-PRP

Which PRP is preferred for knee OA: Leukocyte-Rich PRP (LR-PRP) or Leukocyte-Poor PRP (LP-PRP)?

Speaker: Laura de Girolamo

Publication: ESSKA ORBIT Consensus Report

Preparation: platelet number/ concentration range of PRP injections in OA knee

What is the recommended platelet number/concentration range for PRP injections in knee OA?

Speaker: Laura de Girolamo

Publication: ESSKA ORBIT Consensus Report

Preparation: recommend volume of PRP injections in knee OA

What is the recommended volume of PRP to inject into a knee for the treatment of knee OA?

Speaker: Thomas Tischer

Publication: ESSKA ORBIT Consensus Report

Protocol: number of injections

How many injections of PRP are recommended for the treatment of knee OA?

Speaker: Lior Laver

Publication: ESSKA ORBIT Consensus Report

Protocol: interval between injections

When using a treatment protocol with more than one injection for knee OA, what is the recommended interval between each injection of PRP?

Speaker: Rodica Marinescu

Find Publication: ESSKA ORBIT Consensus Report

Protocol: use of NSAIDS

Are non steroidal anti-inflammatory drugs (NSAIDs) allowed around PRP use?

Speaker: Baris Kocaoglu

Publication: ESSKA ORBIT Consensus Report

Protocol: use of inter-articular local anesthetics

Should intra-articular local anesthetics be used when injecting PRP?

Speaker: Ramon Cugat

Publication: ESSKA ORBIT Consensus Report

Protocol: use of Antibiotics

Is Antibiotics administration recommended around PRP use?

Speaker: Ramon Cugat

Publication: ESSKA ORBIT Consensus Report

Protocol: patient's behavior as treatment factor

Is fasting recommended before PRP use? Is there any other patient behaviour that could affect the treatment?

Speaker: Rodica Marinescu

Publication: ESSKA ORBIT Consensus Report

Protocol: synergistic effects of PRP and HA

Does PRP and HA have a synergistic effect?

Speaker: Michael Iosifidis

Publication: ESSKA ORBIT Consensus Report

Protocol: synergies between PRP and cell-based therapy for knee OA

Is there any synergy between PRPs and cell-based therapies for knee OA?

Speaker: Laura de Girolamo

Publication: ESSKA ORBIT Consensus Report